.pdf-panel-toolbar{border-bottom:1px solid var(--border);background:linear-gradient(to bottom, var(--surface-2), var(--surface));flex-wrap:wrap;align-items:center;gap:.5rem;padding:.65rem .85rem;display:flex}.pdf-panel-toolbar.pdf-panel-toolbar--wrap{row-gap:.65rem}.pdf-panel-toolbar .secondary,.pdf-panel-toolbar label.pick,.pdf-panel-toolbar button{font:inherit;cursor:pointer;border:1px solid var(--border);border-radius:var(--radius-xs);background:var(--surface);color:var(--text);box-shadow:var(--shadow-sm);padding:.38rem .75rem;font-size:12px;font-weight:500;transition:background .14s,border-color .14s,box-shadow .14s,transform 80ms}.pdf-panel-toolbar .secondary:hover,.pdf-panel-toolbar label.pick:hover{background:var(--surface-3)}.pdf-panel-toolbar .secondary:active:not(:disabled),.pdf-panel-toolbar label.pick:active,.pdf-panel-toolbar button:active:not(:disabled){background:var(--surface-2);border-color:var(--border-strong);filter:none;transform:translateY(1px);box-shadow:inset 0 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.45rem;font-size:13px}.pdf-panel-toolbar .pdf-find-bar .pdf-find-input:focus{box-shadow:none;border-color:#0000;outline:none}.pdf-panel-toolbar .pdf-find-bar .pdf-find-input:disabled{color:var(--text-muted);background:0 0}.pdf-panel-toolbar .pdf-find-bar .pdf-find-status{font-variant-numeric:tabular-nums;min-width:1.75rem;color:var(--text-muted);text-align:center;white-space:nowrap;flex:none;align-self:center;padding:0 .15rem;font-size:11px;font-weight:600}.pdf-panel-toolbar .pdf-find-bar .pdf-find-status:not(:empty){color:var(--accent-hover)}.pdf-find-nav-btn{border:none;border-left:1px solid var(--border);width:1.65rem;min-height:1.65rem;color:var(--text-muted);font:inherit;cursor:pointer;background:0 0;border-radius:0;flex:none;justify-content:center;align-items:center;margin:0;padding:0;font-size:12px;font-weight:700;line-height:1;transition:background .12s,color .12s;display:inline-flex}.pdf-find-nav-btn:hover:not(:disabled){background:var(--surface-3);color:var(--text)}.pdf-find-nav-btn:active:not(:disabled){background:var(--surface-2)}.pdf-find-nav-btn:focus-visible{box-shadow:inset 0 0 0 2px var(--focus-ring);outline:none}.pdf-find-nav-btn:disabled{opacity:.35;cursor:not-allowed}.pdf-find-clear-hl-btn{letter-spacing:-.02em;font-size:11px}.pdf-find-clear-hl-btn:not(:disabled):hover{color:var(--accent-hover)}.pdf-panel-toolbar .pdf-find-input{resize:none;width:auto;min-width:100px;max-width:220px;font:inherit;border:1px solid var(--border);border-radius:var(--radius-xs);background:var(--surface);color:var(--text);box-shadow:var(--shadow-sm);flex:120px;padding:.38rem .65rem;font-size:13px;transition:border-color .15s,box-shadow .15s}.pdf-panel-toolbar .pdf-find-input:focus{box-shadow:0 0 0 3px var(--focus-ring);border-color:#2dd4bfb3;outline:none}.pdf-panel-toolbar .pdf-find-input:disabled{background:var(--surface-3);color:var(--text-muted)}.pdf-panel-toolbar .pdf-find-status{min-width:2rem;color:var(--accent-hover);flex:auto;font-size:12px;font-weight:500}.pdf-panel-view-tab.pdf-panel-view-tab--active{color:var(--accent-hover);background:var(--accent-soft);border-color:#2dd4bf8c}.pdf-panel-view-tab:disabled{opacity:.42;cursor:not-allowed}.pdf-status{color:var(--text-muted);padding:.35rem .85rem .5rem;font-size:12px;font-weight:500}.pdf-view-body{flex-direction:column;flex:auto;min-height:0;display:flex;position:relative;overflow:hidden}.pdf-pages{scrollbar-gutter:stable;background:var(--surface-3);flex:auto;padding:.5rem .65rem 1rem;overflow:hidden auto}.pdf-view-body--readable .pdf-pages,.pdf-view-body--pages .pdf-text-pane,.pdf-pages[hidden]{display:none!important}[data-theme=dark] .pdf-panel-toolbar{background:linear-gradient(#334155,#1e293b)}[data-theme=dark] .pdf-panel-toolbar .secondary:active:not(:disabled),[data-theme=dark] .pdf-panel-toolbar label.pick:active,[data-theme=dark] .pdf-panel-toolbar button:active:not(:disabled),[data-theme=dark] .pdf-text-pane-toolbar .secondary:active:not(:disabled),[data-theme=dark] .pdf-text-pane-toolbar button:active:not(:disabled){background:#475569a6;border-color:#94a3b8;box-shadow:inset 0 3px 14px #00000073}[data-theme=dark] .pdf-text-pane-toolbar{background:linear-gradient(#334155,#1e293b)}[data-theme=dark] .pdf-pages{background:#0f172a}.pdf-text-pane{background:var(--surface-3);--pdf-readable-font-size:13px;flex-direction:column;flex:auto;width:100%;min-height:0;display:flex;overflow:hidden}.pdf-text-size{align-items:center;gap:.3rem;display:inline-flex}.pdf-text-size-label{color:var(--text-muted);text-transform:uppercase;letter-spacing:.04em;font-size:11px;font-weight:600}.pdf-text-size-value{text-align:center;min-width:2.6rem;color:var(--text);font-size:12px;font-weight:600}.pdf-text-pane-toolbar .pdf-text-size button{min-width:1.9rem;padding:.3rem .45rem;line-height:1}.pdf-auto-ocr-toggle{color:var(--text-muted);white-space:nowrap;cursor:pointer;-webkit-user-select:none;user-select:none;flex-shrink:0;align-items:center;gap:.3rem;font-size:12px;font-weight:600;display:inline-flex}.pdf-auto-ocr-toggle input{cursor:pointer;accent-color:var(--accent,#4f8cff);margin:0}.pdf-text-pane-toolbar{border-bottom:1px solid var(--border);background:linear-gradient(to bottom, var(--surface-2), var(--surface));flex-wrap:wrap;align-items:center;gap:.5rem;padding:.65rem .85rem;font-size:12px;display:flex}.pdf-text-pane-toolbar .secondary,.pdf-text-pane-toolbar button{font:inherit;cursor:pointer;border:1px solid var(--border);border-radius:var(--radius-xs);background:var(--surface);color:var(--text);box-shadow:var(--shadow-sm);padding:.38rem .75rem;font-size:12px;font-weight:500;transition:background .14s,border-color .14s,box-shadow .14s,transform 80ms}.pdf-text-pane-toolbar .secondary:hover:not(:disabled),.pdf-text-pane-toolbar button:hover:not(:disabled){background:var(--surface-3)}.pdf-text-pane-toolbar .secondary:active:not(:disabled),.pdf-text-pane-toolbar button:active:not(:disabled){background:var(--surface-2);border-color:var(--border-strong);filter:none;transform:translateY(1px);box-shadow:inset 0 3px 8px #0f172a1a}.pdf-text-pane-toolbar .secondary:disabled,.pdf-text-pane-toolbar button:disabled{opacity:.55;cursor:not-allowed}.pdf-text-pane-meta{min-width:0;color:var(--text-muted);flex:auto;line-height:1.35}.pdf-output-close{border:1px solid var(--border);width:22px;height:22px;color:var(--text-muted);cursor:pointer;background:0 0;border-radius:6px;flex:none;justify-content:center;align-self:center;align-items:center;margin-left:auto;padding:0;font-size:16px;line-height:1;transition:background .12s,color .12s,border-color .12s;display:inline-flex}.pdf-output-close:hover,.pdf-output-close:focus-visible{background:var(--surface-2);color:var(--text);border-color:var(--accent);outline:none}.pdf-plaintext-stack{border-radius:8px}.pdf-plaintext-stack--locate-pulse{animation:1.2s pdfLocatePulse}@keyframes pdfLocatePulse{0%{box-shadow:0 0 #38bdf800}20%{box-shadow:0 0 0 3px #38bdf88c}to{box-shadow:0 0 #38bdf800}}#pdf-format-output-wrap{flex:auto}.pdf-fmt-output{background:var(--surface);min-height:0;color:var(--text);flex:auto;margin:0;padding:.5rem .85rem .75rem;font-size:13px;line-height:1.5;overflow:auto}.pdf-fmt-output:focus-visible{outline:2px solid var(--accent);outline-offset:-2px}.pdf-fmt-head{color:var(--text);letter-spacing:.01em;margin:.6rem 0 .2rem;font-size:.92em;font-weight:700}.pdf-fmt-head:first-child{margin-top:0}.pdf-fmt-row{justify-content:space-between;align-items:baseline;gap:.5rem;padding:.12rem 0;display:flex}.pdf-fmt-text{white-space:pre-wrap;word-break:break-word;flex:auto;min-width:0}.pdf-fmt-row--empty{opacity:.82}.pdf-fmt-text--empty{color:var(--text-muted);font-style:italic}.pdf-fmt-source-btn{font:inherit;border:1px solid var(--border);background:var(--surface-2);color:var(--text-muted);cursor:pointer;white-space:nowrap;opacity:.7;border-radius:999px;flex:none;padding:.05rem .45rem;font-size:.72rem;line-height:1.3;transition:opacity .12s,border-color .12s,color .12s}.pdf-fmt-row:hover .pdf-fmt-source-btn,.pdf-fmt-source-btn:focus-visible{opacity:1}.pdf-fmt-source-btn:hover{border-color:var(--accent);color:var(--text)}.pdf-phi-risk{border-top:1px solid var(--border);background:var(--surface-2);flex-wrap:wrap;flex:none;align-items:center;gap:.35rem;max-height:30%;padding:.5rem .85rem;font-size:12px;display:flex;overflow-y:auto}.pdf-phi-risk[hidden]{display:none!important}.pdf-phi-risk-head{color:var(--status-review,#f59e0b);margin-right:.15rem;font-weight:600}.pdf-phi-risk-ok{color:var(--text-muted)}.pdf-phi-risk-chip{font:inherit;cursor:pointer;border:1px solid var(--border);background:var(--surface);color:var(--text);text-overflow:ellipsis;white-space:nowrap;border-radius:999px;max-width:100%;padding:.1rem .5rem;line-height:1.4;overflow:hidden}.pdf-phi-risk-chip:hover{border-color:var(--accent);background:color-mix(in srgb, var(--accent) 12%, var(--surface))}.pdf-phi-risk-chip.pdf-phi-risk-name{border-color:color-mix(in srgb, #ef4444 55%, var(--border))}.pdf-phi-risk-chip.pdf-phi-risk-id,.pdf-phi-risk-chip.pdf-phi-risk-number{border-color:color-mix(in srgb, #f59e0b 55%, var(--border))}.pdf-plaintext-stack{flex:auto;min-width:0;min-height:0;display:grid;position:relative;overflow:hidden}.pdf-plaintext-backdrop-wrap{pointer-events:none;z-index:0;grid-area:1/1;overflow:hidden}.pdf-plaintext-backdrop-inner{box-sizing:border-box;white-space:pre-wrap;word-wrap:break-word;overflow-wrap:break-word;min-height:100%;font-family:inherit;font-size:var(--pdf-readable-font-size,13px);color:var(--text);background:var(--surface);will-change:transform;margin:0;padding:.65rem .85rem calc(.65rem + 1.5em);line-height:1.5;transform:translate(0,0)}.pdf-readable-insert-marks{z-index:2;pointer-events:none;grid-area:1/1;min-width:0;min-height:0;overflow:hidden}.pdf-readable-insert-marks-inner{box-sizing:border-box;white-space:pre-wrap;word-wrap:break-word;overflow-wrap:break-word;min-height:100%;font-family:inherit;font-size:var(--pdf-readable-font-size,13px);color:#0000;will-change:transform;margin:0;padding:.65rem .85rem calc(.65rem + 1.5em);line-height:1.5;transform:translate(0,0)}.pdf-readable-insert-hit{color:#0000;background:#2dd4bf6b;border-radius:3px;outline:1px solid #0d94888c}[data-theme=dark] .pdf-readable-insert-hit{background:#2dd4bf57;outline-color:#0d94887a}.pdf-plaintext-stack--finding .pdf-plaintext-view{caret-color:var(--accent-hover);color:#0000!important;background:0 0!important}.pdf-plaintext-stack--finding .pdf-plaintext-view::selection{background:#38bdf873}.pdf-readable-find-hit{color:inherit;background:#38bdf859;border-radius:3px;outline:1px solid #0ea5e9cc}.pdf-readable-find-hit--active{background:#0ea5e994;outline:2px solid #0284c7f2;box-shadow:0 0 0 1px #ffffff80}[data-theme=dark] .pdf-plaintext-stack--finding .pdf-plaintext-view::selection{background:#38bdf861}.pdf-plaintext-stack--fh-source .pdf-plaintext-view{caret-color:var(--accent-hover);color:#0000!important;background:0 0!important}.pdf-plaintext-stack--fh-source 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#ffffff73}.pdf-plaintext-view{z-index:1;resize:none;box-sizing:border-box;width:100%;height:100%;min-height:0;font-family:inherit;font-size:var(--pdf-readable-font-size,13px);background:var(--surface);color:var(--text);caret-color:var(--accent-hover);cursor:text;-webkit-user-select:text;user-select:text;border:none;border-radius:0;grid-area:1/1;margin:0;padding:.65rem .85rem calc(.65rem + 1.5em);scroll-padding-bottom:1.5em;line-height:1.5;overflow:auto}.pdf-plaintext-view::selection{background:#2dd4bf59}.pdf-plaintext-view:focus-visible{box-shadow:inset 0 0 0 2px var(--focus-ring);outline:none}button.hpo-panel-btn{font:inherit;border:1px solid var(--border);border-radius:var(--radius-xs);background:var(--surface);min-height:0;color:var(--text);box-shadow:var(--shadow-sm);justify-content:center;align-items:center;gap:.35rem;padding:.38rem .75rem;font-size:12px;font-weight:500;line-height:1.25;transition:background .14s,border-color .14s,box-shadow .14s,transform 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.55rem;font-size:11px;font-weight:700}.goi-gene-chip--valid{color:#047857;background:#10b9811a;border-color:#10b9818c}.goi-gene-chip--alias{color:#0d9488;background:#2dd4bf1f;border-color:#2dd4bf8c}.goi-gene-chip--unknown{color:#be123c;background:#f43f5e1a;border-color:#f43f5e8c}.goi-gene-chip--na{border-color:var(--border);background:var(--surface-2);color:var(--text-muted);font-weight:600}[data-theme=dark] .goi-gene-chip--valid{color:#6ee7b7}[data-theme=dark] .goi-gene-chip--alias{color:#5eead4}[data-theme=dark] .goi-gene-chip--unknown{color:#fb7185}.icd-code-chip{border:1px solid var(--border);border-radius:var(--radius-xs);background:var(--surface);color:var(--text);box-shadow:var(--shadow-sm);padding:.25rem .55rem;font-size:11px;font-weight:700;transition:background .12s,border-color .12s,box-shadow .12s,transform 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